Adela Capilnasiu

I acquired my BSc in Applied and Computational Mathematics in Germany, at Jacobs University Bremen.  My undergraduate project, “Modelling blood circulation in sinusoids”, was developed in partnership with the medical research institute Fraunhofer MEVIS, under the supervision of Prof. Tobias Preusser.

Further on, I chose to do an MSc in Applied Mathematics at Imperial College London. My project focused on “Reversing Neurovascular Coupling Models” under the supervision of Dr. Nick Jones. Having gained experience within mathematical modelling for biomedical applications, I decided to pursue a PhD at the Centre for Doctoral Training in Medical Imaging at King’s College London. Under the supervision of Dr. David Nordsletten and Prof. Ralph Sinkus, I am investigating a biomechanical approach to characterise and distinguish fibrosis from inflammation in chronic diseases of the liver. More specifically, magnetic resonance elastography (MRE) has shown promising results in characterising and staging liver inflammation and fibrosis. However, MRE measurements can be biased by large deformations. My current aim is to model the nonlinear viscoelastic behaviour of the liver using classic rheology and to combine it with knowledge on the deformation in order to eliminate the deformation bias. This would enable an accurate interpretation of liver biomechanical properties from MRE measurements.

Research interests

  • Mathematical modelling
  • soft tissue biomechanics
  • nonlinear mechanics
  • magnetic resonance elastography